About Silantes

Silantes - Stable Isotope Labeled Biomolecules

 

We produce and distribute uniformly and partially labeled biomolecules. These are +98% isotopically enriched in each variation of the stable isotopes 2H, 13C and 15N.

With this portfolio, we serve both applications nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (proteomics) with products and solutions that lead up to precise results. Our vision is to broaden the applications for stable isotope labeled biomolecules.

 

Silantes technology

Silantes uses a new biotechnological approach to produce biomolecules such as amino acids, nucleotides, peptides, proteins and DNA labeled with the stable isotopes 2H and 13C and 15N.

This technology was developed in 1998 by Dr. Hermann Heumann in the German Max-Planck-Institute of Biochemistry - the birth of Silantes.

The technology exploits the fact that chemolithoautotrophic bacteria can metabolise inorganic carbon in a pathway similar to that of green plants. Chemolithoautotrophic bacteria combine the advantage of green plants of being able to assimilate COwith the advantage that bacteria are more productive and are also capable of expressing heterologous proteins.

The labeled chemolithoautotrophic bacteria cells are used as a factory to produce the stable isotope labeled biomolecules of choice. This pioneering technology provides an outstanding homogeneity of components labeled with stable isotopes, especially in the area of triple labeled (2H, 13C and 15N) biomolecules.

 

Advantages for our customers

As a Max-Planck-Institute for Biochemistry spin-off, we know from personal experience which criteria to satisfy for a successful research project.

  • Silantes technology for in vivo enrichment of stable isotopes in biomolecules is vastly superior to established methods with respect to reliability, speed, quality, versatility and cost - For our high quality products, we guarantee a fair price as well as a constant delivery capacity and reliability.
  • If you are facing special tasks, Silantes is able to align the production to your needs and requirements. With this mindset, we conduced a great number of prestigious projects to success.
  • Silantes employs staff of highly skilled scientists from the fields of molecular biology, microbiology, biochemistry and biotechnology who can provide competent and customer-orientated advice and solutions to the needs of science and industry.
  • Our comprehensive range of services is unique world-wide.

We look forward to discussing your special applications with you and assisting you in finding optimal solutions.