Stable isotope-labeled nucleotides are essential tools for advancing RNA and DNA NMR spectroscopy, enabling precise resonance assignment and deeper insights into structure, dynamics, and molecular interactions. The right labeling strategy can improve spectral resolution while keeping research costs under control.

Unlock new possibilities in RNA and DNA NMR with ¹³C-labeled nucleosides and nucleotides.
Improve resonance assignment through ¹H–¹³C correlation experiments.
Gain insights into ribose conformations and RNA backbone dynamics.
Choose carbon labeling when nitrogen labeling is not required.
Achieve these benefits at the same price as ¹⁵N labeling.

Make the ¹³C Shift and experience the benefits of:

Enhanced RNA NMR assignments: ¹³C labeling enables ¹H–¹³C correlation experiments for improved spectral resolution and more reliable assignment of ribose resonances, supporting the analysis of RNA backbone dynamics and structure.

Cost-effective labeling strategy: Get the benefits of carbon labeling at the same price as ¹⁵N labeling and approximately half the cost of ¹³C,¹⁵N labeling when nitrogen labeling is not required.