SILAC is based on metabolic labelling with stable isotopes in the cell culture medium and living animals. This enables accurate quantitative analysis of the cellular proteome and its posttranslational modifications … Read more
The incorporation of stable isotopes into nucleic acids provides a range of advantages that have unlocked new avenues for exploring the fundamental properties and behaviors of these essential biological molecules. … Read more
Proteomics is the large-scale study of proteins, particularly their structures, functions, and roles in living organisms. Derived from the term ‘proteome,’ which refers to the entire protein complement of a … Read more
Proteomics focuses on the complete set of proteins expressed by a genome, including their quantities, modifications, interactions, and functions, providing a deeper understanding of cell behavior, disease mechanisms, and potential … Read more
In a previous post, we covered quantitative proteomics and how it has emerged as an indispensable tool in modern biological research. The methodology helps scientists to understand the complexities of … Read more
