252923922
Lysine(6)-labeled Mouse Thymus

Lysine(6)-labeled Mouse Thymus

3.600 € plus VAT, plus delivery

Quantity: 100mg

In stock

SKU: 252923922 Categories: , , , ,

Description

– Isotopic enrichment for 13C-Lysine > 97 atom %

Specifications:

– Strain: C57BL/6

– 13C-Lys-labeled for at least 2 generations (F2)

– This product is a wet tissue

Dry ice shipment required.

Silantes GmbH provides metabolically labeled tissues of mice fed with labeled diets produced and developed in-house.

References

Silantes SILAM amino acid mouse diets in scientific publications:

โ€ข Silantes Lys6-SILAM diet (Complete labeling of oocytes): Harasimov, K., Gorry, R. L., Welp, L. M., Penir, S. M., Horokhovskyi, Y., Cheng, S., Takaoka, K., Stรผtzer, A., Frombach, A., Tavares, A. L. T., Raabe, M., Haag, S., Saha, D., Grewe, K., Schipper, V., Rizzoli, S. O., Urlaub, H., Liepe, J., & Schuh, M. (2024). The maintenance of oocytes in the mammalian ovary involves extreme protein longevity. Nature Cell Biology, 26(7), 1124โ€“1138. https://doi.org/10.1038/s41556-024-01442-7
Silantes SILAM 13C and 15N mouse diets in scientific publications:

โ€ข Silantes 15N SILAM diet (Imaging using NanoSims, time dependent proteomics of retina tissue): Bonnin, E. A., Fornasiero, E. F., Lange, F., Turck, C. W., & Rizzoli, S. O. (2021). NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover. BMC Molecular and Cell Biology, 22(1). https://doi.org/10.1186/s12860-020-00339-1

โ€ข Silantes 15N SILAM diet (time dependent targeted metabolomics and proteomics): Weckmann, K., Deery, M. J., Howard, J. A., Feret, R., Asara, J. M., Dethloff, F., Filiou, M. D., Labermaier, C., Maccarrone, G., Lilley, K. S., Mueller, M., & Turck, C. W. (2018). Ketamineโ€™s effects on the glutamatergic and GABAergic systems: A proteomics and metabolomics study in mice. Complex Psychiatry, 5(1), 42โ€“51. https://doi.org/10.1159/000493425

โ€ข Silantes 15N-SILAM diet (time dependent targeted metabolomics and proteomics, brain tissue, hippocampus tissue, blood tissue, plasma): Zhang, Y., Filiou, M. D., Reckow, S., Gormanns, P., Maccarrone, G., Kessler, M. S., Frank, E., Hambsch, B., Holsboer, F., Landgraf, R., & Turck, C. W. (2011). Proteomic and metabolomic profiling of a trait anxiety mouse model implicate affected pathways. Molecular & Cellular Proteomics, 10(12). https://doi.org/10.1074/mcp.m111.008110

โ€ข Silantes 15N-SILAM diet (complete labeling of brain tissue, proteomics): Klingener, Michael, et al. โ€œN-Cadherin Promotes Recruitment and Migration of Neural Progenitor Cells from the SVZ Neural Stem Cell Niche into Demyelinated Lesions.โ€ The Journal of Neuroscience, vol. 34, no. 29, 16 July 2014, pp. 9590โ€“9606, https://doi.org/10.1523/jneurosci.3699-13.2014 .

โ€ข Silantes 15N-SILAM diet (time dependent labeling in slowly proliferative tissues, proteomics): John Hasper, Kevin Welle, Jennifer Hryhorenko, Sina Ghaemmaghami, Abigail Buchwalter Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes. Mol Syst Biol. (2023) 19: e11393 https://doi.org/10.15252/msb.202211393
Relevant blog articles:

โ€ข Quantitative Proteomics Explained: Techniques, Applications, and Challenges: https://www.silantes.com/guide-to-quantitative-proteomics-techniques-applications-and-challenges/

โ€ข Quantitative Proteomics: Comparing the Big Three โ€“ iTRAQ, TMT, and SILAC: https://www.silantes.com/itraq-tmt-silac/

โ€ข Quantitative Proteomics: Label-Free versus Label-Based Methods: https://www.silantes.com/label-vs-label-free-quantitative-proteomics/

โ€ข Understanding the Role of Mass Spectrometry in Metabolomics: https://www.silantes.com/mass-spectrometry-metabolomics/

โ€ข Understanding Proteomics: A Comprehensive Guide to the Various Types: https://www.silantes.com/types-of-proteomics/

โ€ข A Proteomics and Metabolomics Study using 15N-SILAM mouse diet: https://www.silantes.com/stable-isotope-labelling-in-mammals/
Relevant webinars:

โ€ข Proteomics using SILAC presented by Prof. Dr. Marcus Krรผger: https://www.youtube.com/watch?v=TY6iV8_43iA

โ€ข Multiplexing with isotopic labels for DDA and DIA in MaxQuant presented by Dr. Jรผrgen Cox: https://www.youtube.com/watch?v=-Yddv7ehYsk

โ€ข Stable Isotope Labeling of Mammals presented by Dr. Christoph Turck: https://www.youtube.com/watch?v=BQWvLdILjCA

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