Biomasses

We offer stable isotope labeling of various organisms. Our customized closed systems allow us to label all molecules in the biomass with an enrichment of over 98 atom % for the respective isotopes ²H, ¹³C and ¹⁵N. The biomasses are therefore an optimal source for isotope-labeled molecules.

Furthermore, biomasses can be used as a dietary basis to incorporate stable isotopes through metabolic pathways into organisms.

Use-cases of the biomasses from Silantes:

• Downey, K., Michal, C. A., Bermel, W., Jenne, A., Soong, R., Decker, V., Busse, F., Goerling, B., Heumann, H., Boenisch, H., Gundy, M., & Simpson, A. J. (2023). Targeted Compound Selection with Increased Sensitivity in 13C-Enriched Biological and Environmental Samples Using 13C-DREAMTIME in Both High-Field and Low-Field NMR. Analytical Chemistry, 95(16), 6709–6717. https://doi.org/10.1021/acs.analchem.3c00445
• Anaraki, M. T., Lysak, D. H., Soong, R., Simpson, M. J., Spraul, M., Bermel, W., Heumann, H., Gundy, M., Boenisch, H., & Simpson, A. J. (2020). NMR assignment of thein vivodaphnia magna metabolome. Analyst, 145(17), 5787–5800. NMR assignment of the in vivo daphnia magna metabolome
• Lane, D., Soong, R., Bermel, W., Ning, P., Majumdar, R. D., Tabatabaei-Anaraki, M., Heumann, H., Gundy, M., Bönisch, H., Mobarhan, Y. L., Simpson, M. J., & Simpson, A. J. (2019). Selective Amino Acid-Only In Vivo NMR: a powerful tool to follow stress processes. ACS Omega, 4(5), 9017–9028. https://doi.org/10.1021/acsomega.9b00931
• Biswas, R. G., Fortier‐McGill, B., Akhter, M., Soong, R., Ning, P., Bastawrous, M., Jenne, A., Schmidig, D., De Castro, P., Gräf, S., Kuehn, T., Busse, F., Struppe, J., Fey, M., Heumann, H., Boenisch, H., Gundy, M., Simpson, M. J., & Simpson, A. J. (2020). Ex vivo Comprehensive Multiphase NMR of whole organisms: A complementary tool to in vivo NMR. Analytica Chimica Acta: X, 6, 100051. https://doi.org/10.1016/j.acax.2020.100051
• Moxley‐Paquette, V., Wu, B., Lane, D., Bastawrous, M., Ning, P., Soong, R., De Castro, P., Kovačević, I., Frei, T., Stuessi, J., Adwan-Stojilkovic, D. A., Gräf, S., Vincent, F., Schmidig, D., Kuehn, T., Kuemmerle, R., Beck, A., Fey, M., Bermel, W., . . . Simpson, A. J. (2021). Evaluation of double‐tuned single‐sided planar microcoils for the analysis of small 13 C enriched biological samples using 1 H‐ 13 C 2D heteronuclear correlation NMR spectroscopy. Magnetic Resonance in Chemistry, 60(3), 386–397. https://doi.org/10.1002/mrc.5227

In addition to the isotope-labeled biomasses listed in this webshop, we also offer a custom synthesis service. Please contact our customer service.